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KMID : 0870420090130020114
Korean Journal of Hepato-Biliary-Pancreatic Surgery
2009 Volume.13 No. 2 p.114 ~ p.119
Composite Large Cell Neuroendocrine Carcinoma and Adenocarcinoma of the Ampulla of Vater
Son Bo-Sung

Han Nam-Ik
Nam Yu-Hee
Lee Hee-Jeong
Park Il-Young
Lee Jin-Ah
Abstract
Large Cell Neuroendocrine Tumors (LCNEC) in the ampulla of Vater are extremely rare. Thisreport addresses a case of concurrent LCNEC and adenocarcinoma in the ampulla of Vater. A60-year-old male patient experienced fever, body chills and jaundice. He had a periampullaryulcerative lesion and underwent radical pancreaticoduodenectomy. Histopathologically, thetumor consisted of an LCNEC component and an adenocarcinoma component. Simultaneous
LCNEC and adenocarcinoma has been reported in a few cases. Our patient had a coexisting LCNEC and an adenocarcinoma of the ampulla of Vater. We also present a review of the literature.
KEYWORD
Large Cell Neuroendocrine Carcinoma, Large Cell Neuroendocrine Tumors (LCNEC) in the ampulla of Vater are extremely rare. ThisAdenocarcinoma, Ampulla of Vater
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